Correlation between clinical and histopathologic diagnoses of oral lichen planus based on modified WHO diagnostic criteria
Received 21 September 2008; received in revised form 7 February 2009; accepted 9 February 2009.
Objective
We studied the correlation between the clinical and histopathologic diagnoses of oral lichen planus (OLP) based on the modified World Health Organization (WHO) diagnostic criteria (2003).
Study design
First, 4 oral pathologists and 4 clinicians reviewed and categorized 62 microscopic slides and clinical photographs based on WHO 1978 criteria, and then based on modified WHO definition. The number of photographs and microscopic slides in which all clinicians and all pathologists agreed were calculated and compared.
Results
Based on 1978 criteria, in 68% of cases in which all clinicians agreed about the diagnosis of OLP, all pathologists agreed about the diagnosis of OLP. Conversely, in 79% of cases in which all pathologists agreed on the diagnosis of OLP, all clinicians agreed on the diagnosis of OLP. Based on modified criteria, in 93.87% of cases in which all clinicians agreed on the diagnosis of OLP, all pathologists agreed on the diagnosis of OLP. Similarly, in 95.83% of the cases in which all pathologists agreed about the diagnosis of OLP, all clinicians agreed about the diagnosis of OLP.
Conclusion
Results show higher clinicopathologic correlation in the diagnosis of OLP based on the modified criteria of OLP compared with the 1978 criteria.
aAssistant Professor, Department of Oral Medicine, Kerman School of Dentistry, member of Kerman Oral and Dental Diseases Research Center, Kerman, Iran
bOral Pathology Specialist, Department of Oral Pathology, Kerman School of Dentistry, Kerman, Iran
cAssociate Professor, Department of Oral Medicine, Kerman School of Dentistry, member of Kerman Oral and Dental Diseases Research Center, Kerman, Iran
dDentist, Member of Kerman Oral and Dental Diseases Research Center, Kerman, Iran
Reprint requests: Maryam Rad, DDS, MS, Assistant Professor, Oral Medicine Department, Dental School, Kerman Medical University, Shafa Street, Kerman, Iran
This work was supported by Research Center of Kerman Medical Science.
ABSTRACT