Multifocal myopericytoma in the maxillofacial region: a case report
Received 4 November 2008; received in revised form 14 September 2009; accepted 18 September 2009.
Myopericytoma is a rare mesenchymal neoplasm with perivascular myoid differentiation. Myopericytoma arises most commonly in middle adulthood. The lesion generally involves the distal extremities; however, tumors can also arise at other sites, including the proximal extremities and head and neck. In this case report, a 43-year-old Chinese woman presented with a painless slowly growing nodule in her right cheek. Biopsy revealed a periluminal proliferation of monomorphic oval to spindle-shaped myoid-appearing cells. Immunohistochemistry showed a positive staining for smooth muscle actin. The clinical, pathologic, and immunohistochemical features are discussed. To our knowledge, this is the first case report in the medical literature of multifocal myopericytoma in the maxillofacial region.
aGraduate Student, Department of Oral Pathology, West China College of Stomatology, Sichuan University, Chengdu, China
bProfessor and Chairwoman, Department of Oral Pathology, West China College of Stomatology, Sichuan University, Chengdu, China
cLecturer, Department of Oral Pathology, West China College of Stomatology, Sichuan University, Chengdu, China
dResearcher Fellow, Department of Oral Biology, Indiana University School of Dentistry, Indianapolis, IN, USA
Reprint requests: Yu Chen, DDS, PhD, Professor and Chairwoman, Department of Oral Pathology, West China College of Stomatology, Sichuan University, State Key Laboratory of Oral Diseases, No. 14, 3-section, Renminnan Road, Chengdu 610041, China